CRYSTAL STRUCTURE Kd SERVER        PDB to free energy

[ Log In ]

HOW RELEVANT ARE THESE PREDICTIONS

It will vary. In some cases, the predicted Kds are close to solution based.

PDB (equilibrium) (chains) Kd calculated here Kd experimental Reference
1acb (EI=E+I) (E)
1.42E-12
3.95E-13 Biochem. J. (1991) 280, 27-32
1brs (AD=A+D) (A)
7.12E-14
2.39E-13 J. MoL BioL (1995) 248, 478-486
1buh (AB=A+B) (A)
9.57E-08
8.37E-08 Cell, Vol. 84, 863–874
1dkg (ABD=AB+D) (A,B)
2.22E-06
5.97E-06 Science, 276, 431 (1997)
1ycs (AB=A+B) (A)
2.95E-08
3.05E-08 Science, 274, 1001 (1996)
Many more structures give similar accuracy. However, there is no guarantee that the same accuracy will take place with your PDB, please remain skeptical.


 

 
   
Jobs in Queue: 0
     
  Chain(s) to dissociate from the PDB*
         For example: PDB has chains A,B   You enter: A
  log in to upload your PDB  
  Session
Not logged in
 

   
RUNNING